Some skin does not need more volume or more hydration. It needs to recover: from acne, from laser, from sensitivity, or simply from years of sun.
This page explains Rejuran skin booster treatment in Kuala Lumpur in plain terms. It covers what polynucleotides do, the Rejuran versions, the research, who it suits, Klang Valley market prices, the session, results and how Rejuran compares with other boosters.
Repair, hydrate or lift? The right booster depends on the answer.
To start, this one-minute video from the Rejuran brand’s Hong Kong channel shows how PharmaResearch processes the DNA fragments behind the product.
Source video: REJURAN Hong Kong (brand channel) on YouTube
Quick Answer: Rejuran is an injectable skin booster made by PharmaResearch, a Korean regenerative medicine company. It contains polynucleotides (PN), purified DNA fragments from salmon, placed into the dermis with many tiny injections. PN is thought to support the skin’s own repair, helping texture, redness, fine lines and skin barrier recovery.
PharmaResearch calls its processing method DNA Optimizing Technology (DOT). Rejuran is not a filler and does not reshape the face. Instead of adding volume, it works on skin quality. The maker lists separate versions in its May 2026 company release:
Rejuran is one of several boosters offered at our aesthetic clinic in Kuala Lumpur. The doctor chooses the version, the depth and the dose after examining your skin, not from a fixed menu.
Quick Answer: The evidence is encouraging but still small. Saline-controlled and split-face trials show PN boosters improve pores, fine lines, hydration and acne scars, and speed recovery after needle RF. A 2025 systematic review found consistent benefits with mild side effects, but rated most studies low to moderate in quality.
| Concern studied | Patients | Schedule | Main finding | Study |
|---|---|---|---|---|
| Pores and recovery after needle RF, split-face vs saline | 25 | One 2 ml session right after the RF treatment | Pores, wrinkles and hydration improved more on the PN side at week 6; redness settled faster. Skin thickness did not differ. | Kim, 2026 |
| Eye area, PN vs non-cross-linked HA, double-blind split-face | 27 | Three sessions, 2 weeks apart | Overall scores were similar; PN did better on roughness, pores and elasticity. | Lee et al., 2022 |
| Crow’s feet, single group | 30 | Course of PN injections | Wrinkle grade improved at week 18, with better texture and pores on 3D imaging. | Kim et al., 2022 |
| Moderate to severe acne scars, PN vs saline, double-blind | 20 | Course totalling 4 ml | Only the PN group improved at 1 and 3 months. This used a different PN brand. | Araco & Araco, 2021 |
| Review of 9 PN studies | 219 | Varied | Wrinkles, texture and elasticity improved; side effects mild and short. Study quality low to moderate. | Systematic review, 2025 |
Source: published studies via PubMed. Most were small; only some named Rejuran as the product, and the acne scar trial used another PN brand. Treat these as signs of benefit, not proof for every skin.
Practice data supports the same picture. In a survey of 235 Korean dermatologists, 88% used PN boosters, mostly for fine lines, uneven texture and dry skin. A 2026 survey of 501 dermatologists found 73% used PN for scars. Most chose a three-session course.
Quick Answer: Rejuran usually suits adults with uneven texture, enlarged pores, fine lines, shallow acne scars, redness-prone or sensitive skin, or skin recovering from laser or microneedling. It is a poor fit for deep folds, sagging, active infection, pregnancy or breastfeeding, and anyone allergic to fish or salmon products.
If your main concern is dryness and early laxity, Profhilo treatment may be the better first step. Deeper scars usually need a device as well, such as Sylfirm X RF microneedling. The doctor will tell you if Rejuran is not the right tool.
Quick Answer: Rejuran skin booster treatment in Kuala Lumpur is usually priced per session. In the Klang Valley, one session typically costs RM 1,200–2,500, so a three-session starter course is about RM 3,600–7,500. Rejuran S, Rejuran i and larger areas may be quoted differently after assessment.
| Treatment plan | Note | Market range (bar = upper end) | |
|---|---|---|---|
| One Rejuran session | Per session, face | RM 1,200 – 2,500 | |
| Starter course: three sessions, 2–4 weeks apart | The usual first plan | RM 3,600 – 7,500 | |
| First year: course plus one maintenance session | Four sessions in total | RM 4,800 – 10,000 | |
| For context: Profhilo starter course (two sessions) | RM 2,000 – 4,500 per 2 ml | RM 4,000 – 9,000 | |
| For context: Plenhyage and other PN boosters, per session | Varies by brand and volume | From about RM 928 | |
Illustrative scenario: session counts multiplied by about RM 1,200–2,500 per session, from publicly listed Klang Valley clinic prices, 2025–2026. Not BeauLife’s price list. Your exact quote is given after the consultation.
These are market ranges, not BeauLife’s price list. When comparing quotes, ask:
Not sure whether Rejuran or another booster suits your skin?
Quick Answer: A Rejuran session usually takes under an hour, including time for numbing cream to work. The doctor places small amounts of PN just under the skin in a grid of tiny injections. It stings more than many HA boosters, but numbing cream helps and most people return to normal activities the same day.
Pain is the most common complaint. In a split-face trial, a standard PN booster scored about 5 out of 10 for pain, while a newer, adjusted formula scored about 3.4. A needle-free jet study also reported less pain than needles. Ask which method the doctor will use.
Quick Answer: Most people notice calmer, smoother skin within two to four weeks, and the main change in texture and fine lines builds after the third session. Studies measured gains at six to eighteen weeks. Many people book a maintenance session about every six months to keep the result.
| Time after first session | What usually happens (bar = relative visible change) |
|---|---|
| Day 0 | Small raised bumps along the injection lines, with mild redness. Some people see pinpoint bruises. |
| Days 1–2 | Most bumps flatten. Light make-up is usually fine once the skin has settled. |
| Weeks 2–4 | Skin often feels calmer and more hydrated. The second session is given in this window. |
| Weeks 4–8 | Third session. In a 25-patient trial, pores and hydration were clearly better 6 weeks after one PN session. |
| Weeks 12–18 | The main window to judge texture and fine lines. A crow’s feet study measured gains at week 18. |
| Around month 6 | A common point for one maintenance session if you liked the result. |
Source: Kim, 2026; Kim et al., 2022; the 2024 Korean dermatologist survey; and the maintenance interval commonly quoted in the Klang Valley. Timings are typical ranges, not promises; results vary from person to person.
How long results last depends on age, sun, smoking and skincare; daily SPF helps. Judge Rejuran a month after the final session, not the first week.
Quick Answer: Choose by the main problem. Rejuran suits skin that needs repair, such as texture, redness, scars or post-laser recovery. Profhilo suits dehydrated skin with early laxity and needs the fewest injections. Plenhyage is another PN booster for thin, tired, sensitive skin. Many plans use two of them.
| Feature | Rejuran | Profhilo | Plenhyage |
|---|---|---|---|
| Main ingredient | Polynucleotides (PN) from salmon DNA | High- and low-weight hyaluronic acid (HA) | Polynucleotides (PN) from salmon DNA |
| Main job | Repair: texture, redness, fine lines, scars | Hydration and mild laxity | Repair for thin, tired, sensitive skin |
| Injection pattern | Many tiny micro-injections | 10 points across the face | Many tiny micro-injections |
| Usual starter course | 3 sessions, 2–4 weeks apart | 2 sessions, 4 weeks apart | 3–4 sessions, 21–28 days apart |
| Bumps after treatment | Small bumps for 1–2 days | 10 bumps, flatten within about a day | Small bumps for a few hours |
| Typical Klang Valley market range | RM 1,200 – 2,500 per session | RM 2,000 – 4,500 per 2 ml | From about RM 928 per session |
Source: manufacturer information, published studies via PubMed and publicly listed Klang Valley clinic prices, 2025–2026. Market ranges, not BeauLife’s price list. Courses are typical, not fixed.
Read more on Profhilo for hydration and laxity and Plenhyage skin booster treatment. Another option is RE2O, the newer Korean ECM booster. For fine-line hydration, see Restylane skin boosters.
Quick Answer: Yes. Rejuran is often combined with needle RF, lasers or HA boosters, because PN appears to help the skin recover. In a 25-patient split-face trial, PN given straight after needle RF led to faster redness recovery and better pores and hydration than saline at six weeks.
Rejuran is also sometimes combined with Juvelook collagen booster for pores and texture, or with PICO laser for pigment. The doctor will space treatments so the skin can recover between them.
Quick Answer: Rejuran is generally well tolerated. Common effects are small bumps, redness, swelling, tenderness and pinpoint bruises that usually settle within one to three days. The 2025 systematic review found side effects mild and short-lived. Like any injection, rare risks include infection, nodules and blocked blood vessels.
In a 2026 animal study, PN injected into an artery caused only short-lived flow changes, while cross-linked HA filler caused lasting blockage. That is reassuring, but it is still an animal study. The US Food and Drug Administration advises never buying injectables online. In Malaysia, look for the Medical Device Authority hologram security label on registered devices.
Want to know if Rejuran suits your skin?
Quick Answer: BeauLife provides Rejuran skin booster treatment in Kuala Lumpur at an MOH-registered clinic (KKLIU 1970/2019) operating since 2017, where LCP-certified doctors perform every injectable treatment. The doctor explains which booster suits your skin and gives the full price before treatment, at any of five Klang Valley branches.
Branch addresses and maps are on our contact and branch locations page. You can also read more about BeauLife’s doctors and approach.
Rejuran makes sense if your skin needs repair: rough texture, pores, fine lines, shallow scars, redness or slow recovery after laser. It usually takes three sessions a few weeks apart and works gradually. It stings more than some boosters and leaves small bumps for a day or two. Choose a doctor who explains the evidence, the risks and the full course price first.
In the Klang Valley, Rejuran typically costs RM 1,200 to 2,500 per session. Most people need three sessions, so a starter course is usually RM 3,600 to 7,500. Your exact quote is given after the consultation.
Most plans use three sessions, two to four weeks apart, then maintenance about every six months. Scars may need more sessions.
Many people find it more uncomfortable than HA boosters because of the many small injections. Numbing cream is applied first, and the stinging stops soon after the session.
The small bumps usually flatten within one to two days. Book a session at least a week before an important event.
Yes. Its polynucleotides are purified from salmon DNA. Tell the doctor about any fish allergy before treatment.
Yes. Doctors often give Rejuran after laser or needle RF to help recovery, or alternate it with an HA booster. The doctor will space the treatments safely.
Book your Rejuran consultation
A BeauLife doctor will assess your skin, explain whether Rejuran suits you and its risks, and give you a clear plan and price for the full course before anything starts.
